Wednesday 18 June 2014

Photoswitch biosciences

Photoswitches were conceived at the Nanomedicine Development Center for the Optical Control of Biological Function at UC Berkeley . Discover hundreds of Berkeley startup companies founded to commercialize inventions and software under licenses from IPIRA. Learn about working at Photoswitch Biosciences , Inc. See who you know at Photoswitch Biosciences , Inc.


The most advanced photopharmaceutical research and development is being carried out by California-based company Photoswitch Biosciences.

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License agreement between Max Planck Innovation and Photoswitch Biosciences forms the basis for new platform for identifying and testing novel drug candidates.

Here we report that BENAQ, an improved photoswitch, is 20-fold more potent than DENAQ and persists in restoring visual responses to the retina for almost . CEO of Photoswitch Biosciences , Inc. Photoswitch compounds such as DENAQ confer light-sensitivity on endogenous neuronal ion channels, enabling photocontrol of neuronal activity without genetic manipulation. DENAQ treatment restores both retinal light responses and visual . Startup Industrial Research, Photoswitch Biosciences. Doctoral Research, University of California, Berkeley. Continue Ludwig-Maximilians-Universität (new appointment for Dirk Trauner).


Undergraduate Research, Rensselaer Polytechnic Institute. PM – 3:PM, Stephen Smith, Photoswitch Biosciences Inc. A next generation optical plate reader for capturing data at the speed of membrane biology. PM - 4:PM, Robert Bowser, Gregory W. SAB members and consultants of Photoswitch Bioscience , Inc.


In contrast, small molecule photoswitches enable optical control of neuronal excitability without genetic manipulation. Bautista ( UC Berkeley) for helpful comments, A. Nicke (Max Planck Institute of Brain Research) for the P2Xreceptor clone, A. Conflict of interest statement: E. As shown here, phylloxanthobilins are unique four-stage photoswitches. Which switching mode is turned on is controlled by the molecular environment.

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